CBD has been touted as a potential treatment for a wide range of health issues, but the strongest scientific evidence points to its effectiveness in treating some of the most severe childhood epileptic syndromes, such as Dravet syndrome and Lennox-Gastaut syndrome (LGS). These conditions are often resistant to traditional antiseizure medications. CBD has also been found to have a therapeutic effect, making it useful for managing pain and inflammation. People with chronic pain have reported feeling better after using CBD oil.
It's scientifically proven to help treat headaches, insomnia, mental health disorders, arthritis, and other chronic syndromes. For centuries, people have used marijuana for medical purposes to manage their chronic pain. Now, medical marijuana is associated with CBD, which appears to be a legitimate option. In preliminary animal studies, THC and CBD have shown some similar effects, such as anti-inflammatory and analgesic properties and antioxidants and neuroprotectors.
A retrospective observational study examined the effects of CBD-rich treatment on pain, anxiety, symptoms of depression and well-being in 279 participants over 18 years of age. The study was conducted in a network of clinics dedicated to medical cannabis in Quebec (Canada). In the US, it is legal to sell and buy CBD in one form or another. However, due to federal regulations, it is more difficult to sell it across state lines.
For example, while 300 milligrams of CBD may reduce a person's anxiety, the same person may not feel any relief with a dose of 100 milligrams or 900 milligrams. The success of CBD has been documented by families and children like Charlotte Figi, which has prompted further research into its potential benefits. Most randomized trials studied the effects of a single dose of CBD, making it difficult to compare observed treatment outcomes with chronic dosing clinical settings. Many claims about CBD go beyond the limits of medical evidence, including those related to preparations that purport to prevent cancer or treat Alzheimer's disease.
Controlled clinical settings are needed for future research in order to provide a more complete description of the efficacy of CBD. Zuardi and colleagues used a test that simulates public speaking to demonstrate that prior treatment with a single dose of CBD can reduce associated discomfort in people with social anxiety disorder.11 Because of decades of restrictions on research in the US and the focus of producers on THC, there are very few human studies that analyze CBD and its effects. Research on CBD in the 1970s and 1980s focused on its interaction with other cannabinoids, particularly THC.